Programme

24 Sept
25 Sept
26 Sept
27 Sept
Posters

Wednesday, 24 September

11:00-13:00	Registrations
13:30-14:00	Opening by Felice Cervone (FISV President) and Lucio Luzzatto (FISV past-President) Commemoration of Ferruccio Ritossa by Edoardo Boncinelli
14:00-15:00	Plenary Lecture 1: EMBO LECTURE Giacomo Cavalli (Montpellier, France) Genome regulation by Polycomb proteins and 3D chromosome folding
15:00-17:00	Plenary Symposium 1 Microorganisms and Cancer Chairs: Bianca Colonna, Milena Grossi Teresa Frisan (Stockholm, Sweden) Carcinogenic properties of bacterial genotoxins Marina de Bernard (Padua) Helicobacter pylori infection and Th17 profile in chronic gastritis Massimo Tommasino (Lyon, France) The role of human papillomaviruses in carcinogenesis Massimo Levrero (Rome) Molecular mechanisms of HBV-associated hepatocarcinogenesis
17:30-19:00	Round Table La Tracciabilita Genetica per uomini, animali e piante: aspetti scientifici, economici, giuridici ed etici Coordinatori: Dr Walter Daviddi Tenente Colonnello Giampietro Lago (Ph.D., comandante del R.I.S. di Parma) “Tracciabilità umana” Prof. Andrea Armani (Responsabile Fish Lab e Docente di Ispezione Alimenti di origine Animale, Università di Pisa) “Tracciabilità animali” Prof. Luigi Frusciante (Ordinario di Genetica Agraria, Università di Napoli Federico II) “Tracciabilità vegetali” Prof. Gianluca Brunori (Economista, Ordinario di Economia Agraria, Docente di Bioeconomia, Università di Pisa) “Aspetti economici” Prof. Sergio Bartolommei (Filosofo e Docente di Bioetica all'Universitàdi Pisa) “Aspetti etici”

Thursday, 25 September

9:00-10:00	Plenary lecture 2 Elena Cattaneo (Milan) Huntington, the story of an ancient gene in search of a better future
10:00-10:30	Coffee break
10:30-12:30	Plenary Symposium 2 Modeling cell pathophysiology by integrative network-based association studies Chairs: Gennaro Ciliberto, Ruggero Pardi Andrea Califano (New York, NY, USA) Elucidating non oncogene dependencies in cancer by assembly and interrogation of regulatory networks Diego Di Bernando (Naples) Networking drugs and diseases: a systems biology perspective Gianni Cesareni (Rome) The logic network underlying the anti-cancer activity of metformin: a systems approach Ermanno Rizzi (Milan) Genomic Integration Sites (IS) analysis of virus-based vectors for gene therapy: the Integrome Graziano Martello (Padua) Cracking the naive Pluripotency code Davide Corona (Palermo) Role of the chromatin remodelling factor ISWI intTissue regeneration
12:30-14:30	Lunch & Posters viewing (Session I)
14:30-17:00	Short talks by participants A B C D E F Metabolism and its Regulation in Health and Disease Chairs: Paola Chiarugi, Loredano Pollegioni Santina Bruzzone (Genoa) Impaired increase of plasma abscisic acid in response to oral glucose load in type 2 diabetes and in gestational diabetes Paolo Cirri (Florence) Fibroblasts transfer lipids and proteins to cancer cells through cargo vesicles supporting tumor growth Erika Fiorino (Milan) Histone deacetylases (HDACs) and cholesterol catabolism: effect of HDAC7 deletion on lipid and lipoprotein profile Paolo Porporato (Brussels, Belgium) A mitochondrial switch promotes tumor metastasis Nutrition Biochemistry Chairs: Francesco Bonomi, Silvana Hrelia Cristina Angeloni (Bologna) Neuroprotective effects of sulforaphane on methylglyoxal-induced glycation in SH-SY5Y cell line Maria Cristina Mezzacapo (Caserta) Nutritional values and radical scavenging capacities of lentil (Lens culinaris Medik) seeds in Valle Agricola district, Italy Gianna Ferretti (Ancona) Protective effect of apple polyphenols on methylglyoxal-induced glycation of human High density lipoproteins Stefania Iametti (Milan) Physiological consequences of beta-lactoglobulin adsorption on hydrophobic surfaces: making a bad food allergen even worse? Paola Antonia Corsetto (Milan) Docosahexaenoic acid influences cholesterol metabolism in cancer cells Genomics, Proteomics and System Biology Chairs: Manuela Helmer-Citterich, Tiziana Bonaldi Federica Ciregia (Pisa) Glucagon-like peptide-1 protects INS-1E against palmitate-mediated β-cell dysfunction: a proteomic study Marco Fondi (Florence) Modelling in the cold: genome scale metabolic reconstruction and constraints-based modelling of the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 Alessio Mengoni (Florence) Evolution of regulatory networks in Sinorhizobium meliloti is species- and replicon-specific Angela Messina (Catania) The interactome of human VDAC3 revealed in HeLa cells by affinity purification tag technique Maria Manuela Rigano (Naples) Improvement of the nutritional potential of tomato fruits through pyramiding of favorable alleles Transcription Mechanisms and Networks Chairs: Duccio Cavalieri, Rodolfo Negri Cecilia Battistelli (Rome) DNMT3s and miRs-29 in EMT/MET dynamics: a role for HNF4α Sara Borghi (Bologna) A novel regulatory switch controls the expression of Neisseria meningitidis NHBA at physiologically relevant temperatures Valentina Cappelletti (Trento) Multicellularity in yeast: heat shock proteins as actors of an epigenetic regulatory network Angela Cirigliano (Rome) Impairment of the COP9 signalosome in yeast leads to activation of autophagy Silvia Santopolo (Rome) The Dof protein DAG2 is a positive regulator of the phyB-mediated seed germination process Human Genetic and Genomic Diversity Chairs: Mario Ventura, Antonio Torroni Lucia Pellè (Pisa) A case-control association study suggests a role for CYP2E1 in the susceptibility to thyroid carcinoma Andrea Quagliariello (Bologna) Exploring genetic variability of genes involved in nutrition and thermoregulation processes in european populations Carlo Sidore (Cagliari) Whole genome sequencing of 3,514 individuals from the founder population of Sardinia Roberta Rosa Susca (Ferrara) Y-chromosome and mtDNA diversity in the context of Eurasian language diversity Beniamino Trombetta (Rome) Phylogenetic refinement and SNP-based dating of human MSY haplogroup E Evolution Chairs: Sergio Tofanelli, Giorgio Bertorelle Elena Bitocchi (Ancona) Evolutionary history of common bean (Phaseolus vulgaris L.) Irene Cardinali (Perugia) The horse mitochondrial haplogroup variation in ten Italian local breeds Claudia Catacchio (Bari) Gorilla centromere DNA: an answer to longstanding questions? Chiara Papetti (Bremerhaven, Germany) Population genetics of a pelagic notothenioid fish along the Antarctic Peninsula Claudia Vannini (Pisa) Symbiosis evolution: retracing the tangled path from establishment to obligate association in the Betaproteobacteria-Euplotes relationship Epigenetics and Epigenetic Therapies Chairs: Davide Corona, Lucia Altucci Fabio Coppedè (Pisa) Genetic and environmental factors linked to DNA methylation in colorectal cancer revealed by artificial neural networks Svetlana Danovska (Rome) In vivo selection of JARID histone demethylases inhibitors and their use to enlighten the biological role of these enzymes in yeast and mammalian cells with focus on transcriptional regulation Maria Denaro (Pisa) Genetic and epigenetic implications of the MTHFR gene in cardiovascular disease Stefania Sarno (Padua) Analysis of the interaction between LSD1, lysine-specific demethylase 1, and protein kinase CK2 Andrea Stoccoro (Pisa) Gene specific DNA methylation analysis in peripheral blood as potential biomarker for Alzheimer’s Disease Noncoding RNA Chairs: Massimiliano Pagani, Elisa Caffarelli Valeria Bevilacqua (Rome) A novel long noncoding RNA promoting neural induction of human induced pluripotent stem cells Flavia Biamonte (Catanzaro) MiR-21 over-expression in K562 cells silenced for ferritin heavy chain (FHC) is mediated by oxidative stress Ilaria Laudadio (Rome) RNA interference determines nucleosome occupancy at human Transcription Start Sites by interacting with SWI/SNF complex Ilaria Panzeri (Milan) LincRNAs landscape in human lymphocytes highlights regulation of T cell differentiation by linc-MAF-4 Alberto Passi (Varese) O-GlcNAcylation induces hyaluronan synthase 2 transcription modulating promoter chromatin structure via long non coding RNA Oncogenes and Tumor suppressors Chairs: Milena Grossi, Alberto Inga Paolo Armando Gagliardi (Candiolo) PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction Alberto Inga (Trento) The 5’-untranslated region of p16^INK4a melanoma tumor suppressor acts as a cellular IRES, controls mRNA translation during hypoxic stress, and is a target of YBX1 Alessandra Pollice (Naples) MDM2-mediated degradation of p14ARF: a novel mechanism to control ARF levels in cancer cells Maria Cristina Sorrentino (Naples) Epigenetic role of the N-MYC/LSD1 complex in Neuroblastoma Annaelena Troiano (Naples) YB-1 and ΔNp63α cross-talk in the control of squamous carcinoma cell adhesion and survival Environmental and Molecular Mutagenesis Chairs: Sofia Pavanello, Lucia Migliore Silvestro Conticello (Florence) The RNA editing enzyme APOBEC1 induces somatic mutations and its mutational signature is present in esophageal adenocarcinomas Stefania De Marco (Perugia) Investigation of the cytotoxic, genotoxic and apoptotic activities of trans-cinnamaldehyde: pure compound and botanical matrix (cinnamon tea) Eugenia Dogliotti (Rome) Genetic and environmental influence on the activity of the DNA repair enzyme OGG1: a twin study Giada Frenzilli (Pisa) Potential use of the isoflavonic phytoestrogen genistein in thyroid cancer therapy Teresa Brunetti (Pisa) A panel of tests to evaluate genotoxicity and carcinogenicity induced in vitro by metal oxide nanoparticles Immunology and Host-Pathogen Interaction Chairs: Paolo Visca, Maria Bernardini Gianluca Baldanzi (Novara) Inhibition of Diacylglycerol kinase alpha rescues TCR-induced diacylglycerol signaling and restimulation induced cell death in XLP lymphocytes Anna-Karin Hermansson (Rome) Shigella flexneri induced cell death in human monocyte derived dendritic cells Lisa Lombardi (Pisa) Molecular characterization of a Candida orthopsilosis putative adhesin Valeria Sgambati (Naples) ApoE-AP, a new human antimicrobial peptide with promising anti-inflammatory properties Marina Zoppo (Pisa) Targeted gene disruption to investigate the role of Candida parapsilosis putative adhesins Plant Development and Disease Chairs: Simone Ferrari, Giuseppe Firrao Alessandra Boccaccini (Rome) The Arabidopsis DAG1 protein plays a key role in regulating hormonal balance during seed development Andrea Carucci (Rome) Members of AtCuAO gene family exhibit different tissue-and organ-specific expression patterns during seedling development and distinct responses to hormone or stress treatments Simone Luti (Florence) PAMP activity of cerato-platanin: a proteomic study Maria Benedetta Mattei (Rome) Proteomic insights into oligogalacturonide signalling in plant defence and development Maurizio Trovato (Rome) Dissecting the role of proline in pollen development
17:00-17:30	Coffee break
17:30	Societies' time AGI 17:30 Premio Dottorato AGI/Zanichelli 2014 e presentazione del lavoro premiato 18:00 Assemblea dei Soci AGI SIB Assemblea dei Soci Consegna Premio SIB Consegna Premio Heritage Votazioni per il parziale rinnovo del CD SIBE (Organizzatore: M. Casiraghi) Discussione sul convegno SIBE2015 a Bologna Consegna borse di viaggio e premio per miglior articolo 2013-2014 in biologia evoluzionistica Talk del vincitore del premio Comunicazioni dalla SIBE SIBV 17:30 Lecture e consegna del premio Baccarini Melandri 18:30 Assemblea dei soci SIMA (Organizzatori: M. Bignami, C. Bolognesi) 17:30 Premiazione dei migliori poster 18:00 Assemblea straordinaria dei Soci SIMA SIMGBM (Organizzatori: B. Colonna, E. Ricca) 17:30 Paolo La Colla (Univ. Cagliari): "Dalle cefalosporine agli antivirali" 18:00 Consegna Premi e Presentazioni: Premio Naicons Premio Novartis Premi Tatò e SIMGBM 19.00 Assemblea Ordinaria della Società
20:30	Social dinner (Chiostro Chiesa Santa Maria del Carmine)

Friday, 26 September

9:00-11:00	Plenary Symposium 3 Metabolic changes in tumor cells Chairs: Giancarlo Solaini, Bruno Giardina Muller Fabbri (Los Angeles, CA, USA) MicroRNAs as master regulators of the biology of the tumor microenvironment Paolo Bernardi (Padua) Between life and death: a dual function for the mitochondrial F-ATP synthase Alessandra Baracca (Bologna) Role of the inhibitor protein (IF₁) of the mitochondrial ATP synthase on tumor cells metabolism Paola Chiarugi (Florence) OXPHOS and PKM2 within tumor-stroma interplay: a new druggable synergy Roberto Scatena (Rome) The cancer stem cells hypothesis claims for a re-evaluation of cancer metabolism
11:00-11:30	Coffee break
11:30-13:30	Parallel Symposia I 1. The multiple facets of genome instability Chairs: M. Bignami, A. Antoccia Daniela Cimini (Blacksburg, VA, USA) Causes and effects of karyotype alterations Antonio Musio (Pisa) Mutant cohesin drives chromosomal instability in early colorectal adenomas Francesca Demichelis (Trento) The dynamics of cancer genomes during disease progression Stéphanie Tomé (Paris, France) Triplet repeat instability and human disorders 2. Epigenetics: disturbance or resource for plant improvement? Chairs: C. Conicella, D. Carputo Marie Mirouze (Montpellier, France) The epigenetic guardians of genome stability in plants Pasquale Termolino (Portici) Histone acetylation and sex-specific recombination variation in Arabidopsis thaliana Serena Varotto (Padua) Epigenomics of stress response in maize leaf Emanuele De Paoli (Udine) Challenged from inside and outside: plant epigenetic responses to genomic modifications and environmental cues Emidio Albertini (Perugia) Use of MSAP markers to analyze the effects of abiotic stresses on DNA methylation 3. Biochemistry of intracellular channels, carriers and pores Chairs: Vito De Pinto, A. Moroni Vito De Pinto (Catania) Introduction: distinct biochemical features and functional roles of VDAC isoforms of outer mitochondrial membrane Tatiana Rostovtseva (Bethesda, MD, USA) VDAC and tubulin in regulation of mitochondrial metabolism Gerhard Thiel (Darmstadt, Germany) Using small viral ion channels as a tool to understand protein sorting Ildiko Szabo (Padua) Potassium channel(s) in the inner mitochondrial membrane Giuseppe Fiermonte (Bari) The biochemical function of uncoupling protein 2, unknown until now Cesare Indiveri (Cosenza) Cation transporters in health and disease: novel functions and role as drug targets
13:30-15:30	Lunch & Posters viewing (Session II)
15:30-16:30	Plenary Lecture 3 Stephen Howell (Ames, IA, USA) The unfolded protein response in plants — facing a changing world
16:30-17:00	Coffee break
17:00-19:30	Short talks by participants G H I J K L Cellular Stress, apoptosis and autophagy Chairs: Paola Fortini, Gian Maria Fimia Silvia Cetrullo (Bologna) 3-hydroxytyrosol protects chondrocytes against microRNA-9 increased by oxidative stress Giorgia Foggetti (Genoa) Induction of autophagy by mutant p53-targeting molecules in cancer cells Lorenza Garribba (Rome) The fine tuning of autophagy and differentiation in the skeletal muscle Daniele Lombardo (Messina) Crosstalk between autophagy and apoptosis during HSV-1 replication: possible role of Us11 viral protein Cristina Mazzoni (Rome) mRNA degradation and its effect on cellular lifespan and apoptosis in yeast Protein Synthesis, Degradation and Homeostasis Chairs: Marzia Bianchi, Paola Londei Rita Del Giudice (Naples) Structural perturbations in hereditary amyloidosis: the case of two variants of apoA-I Maria Elena Miranda Banos (Rome) A single-chain variable fragment antibody against Z alpha1-antitrypsin prevents intracellular polymerisation Emanuela Pedrazzini (Milan) Proteostasis of the A. thaliana TPK/KCO channels Daniela Braconi (Siena) HGA-induced aggregation and fibrillogenesis of amyloidogenic proteins: implications in alkaptonuria Alessandro Vitale (Milan) An evolutionary model for protein body formation in the endoplasmic reticulum of cereal endosperm cells Development, Differentiation and Aging Chairs: Marco Bianchi, Giorgio Camilloni Vittorio Abbonante (Pavia) Megakaryocytes express extracellular matrix components Nicoletta Filigheddu (Novara) Unacylated ghrelin promotes skeletal muscle regeneration Liliana Felicia Iannucci (Naples) Silencing of Drosophila H/ACA snoRNP pseudouridine synthase dysregulates key developmental pathways Giuseppe Lupo (Rome) Epigenetic regulation of positional identity in neural progenitors Robert Vignali (Pisa) Hmga2 is required for the neural crest cell EMT and migration in the Xenopus embryo Stem Cells, IPS, Cancer Stem Cells Chairs: Giuseppe Lupo, Eugenia Dogliotti Daniela Capello (Novara) Diacylglycerol kinase alpha contributes to tumorigenicity and invasiveness of cancer stem cells Simona Daniele (Pisa) Role of adenosine receptors in survival and differentiation of glioblastoma stem cells Elisa Paolicchi (Pisa) Role of Polycomb/HIF/VEGF pathway in the etiology of mesothelioma Maria Trincavelli (Pisa) Allosteric modulation of A_2B adenosine receptors favours mesenchymal stem cell differentiation to osteoblasts Environmental Microbiology and Biotechnology Chairs: Roberto De Philippis, Margherita Sosio Alessandra Adessi (Florence) Understanding the role of EPSs in BSCs: study of the physiological response of the phototrophic community to EPS removal Alice Checcucci (Florence) Exploring the genetic basis con competition in bacterial symbionts: the acdS gene in the rhizobium Sinorhizobium meliloti Luca Dall'Osto (Verona) Domestication of the green alga Chlorella sorokiniana: reduction of antenna size improves light-use efficiency in a photobioreactor Chiara Schiraldi (Naples) Biotechnological transformation of hydrocortisone to prednisolone by coupling Streptomyces roseochromogenes and Arthrobacter simplex biocatalytic activities Giulia Spini (Florence) Phenotypic variation of the symbiotic nitrogen-fixing bacterium Sinorhizobium meliloti in response to the plant flavonoid luteolin investigated by Phenotype Microarray Genetic of Microorganisms Chairs: Davide Roncarati, Anna Maria Puglia Emanuele Bosi (Florence) MeDuSa: a multi-draft based scaffolder Rosaria Campilongo (Rome) Towards the characterization of the role of YnfB protein in E.coli Alberto Danielli (Bologna) Helicobacter pylori acid acclimation: ménage à trois at the complex arsR promoter Andrea Moglia (Turin) High yield production of avenanthramide analogous endowed with antioxidant properties Francesco Pini (Villeneuve d'Ascq, France) Cell cycle regulation by CtrA in Sinorhizobium meliloti Chromosome Biology, Cell Division and Cell Cycle Chairs: Silvia Bonaccorsi, Antonio Musio Ivana Colao (Messina) Involvement of ERK1/2 in cell cycle regulation during Herpes Simplex Virus replication Giulia Guarguaglini (Rome) Aurora-A kinase inhibition: mitotic effects and implications for anti-cancer strategies Linda Mannini (Pisa) SMC1B, a new mitotic-specific cohesin component, is involved in gene expression Alice Mazzagatti (Pavia) The sliding behaviour of horse chromosome 11 centromere Isabella Saggio (Rome) AKTIP, an E2 variant enzyme that interacts with lamin, is required for correct telomere maintenance DNA replication, Repair and Recombination Chairs: Pietro Pichierri, Marco Muzi Falconi Francesca Grasso (Rome) Colorectal carcinogenesis and the inflammatory response: a role for the MUTYH DNA glycosylase Antonello Lorenzini (Bologna) A cell culture comparative biology approach to study mechanisms of genome stability and their relevance for species longevity: a newer interpretation of DNA damage induced nuclear foci Valentina Palermo (Rome) WRN phosphorylation by CDK modulates pathway choice to repair DNA double strand breaks after end-resection Martina Stevanoni (Padua) Altered replication timing of the frataxin gene in the presence of the GAA/TTC repeat expansion Micol Tillhon (Pavia) CBP/p300-mediated acetylation of PCNA is required for its chromatin removal and degradation in nucleotide excision repair Neurobiology Chairs: Tommaso Pizzorusso, Elena Battaglioli Santina Cutrupi (Turin) Estrogen regulates neuroglobin transcription in neuronal and non-neuronal cancer cells Cecilia Mannironi (Rome) miR-135a and the regulation of neuronal plasticity under stress conditions Debora Napoli (Pisa) Experience-dependent DNA methylation regulates plasticity in the developing visual cortex Luigi Palmieri (Bari) Mutations in the mitochondrial citrate carrier SLC25A1 are associated with impaired neuromuscular transmission Cell Communication, Cell Adhesion and Membrane Trafficking Chairs: Santina Bruzzone, Luca Primo Valentina Bettio (Novara) Diacylglycerol kinase alpha regulates mitotic spindle orientation during epithelial morphogenesis Eleonora Da Pozzo (Pisa) Synthetic agents for protein dimerization, a bridge between chemistry and biology for protein characterization and potential drug development. Laura di Blasio (Turin) PDK1 regulates focal adhesion disassembly through modulation of αvβ3 integrin endocytosis Nunzia Di Maio (Naples) Dyskerin depletion perturbs cell migration and adhesion in colon cancer cells Tiziana Vigliarolo (Genoa) Abscisic acid transport in human erythrocytes Plant Metabolism and Environmental Stress Chairs: Francesco Licausi, Anna Maria Ranieri Francesca Verrillo (Varese) Proteome of Triticum aestivum cv Bologna affected by free – air CO₂ enrichment Maria Concetta de Pinto (Bari) Involvement of DNA methylation in the control of cell growth during heat stress Stefania Pasqualini (Perugia) Plant response mechanisms to drought and insect pest attack: signals from the roots to the leaves Cristina Sudiro (Padua) Addressing molecular and cellular response mechanisms induced by salt stress in two contrasting salt sensitivity varieties of Italian rice (Oryza sativa ssp. Japonica) Mirko Zaffagnini (Bologna) Unraveling the redox regulation and structure of Calvin-Benson cycle enzymes from Chlamydomonas reinhardtii: from proteomic data to in vitro studies Plant Nutrition Chairs: Maurizio Chiurazzi, Luca Espen Moez Maghrebi (Milan) Sentinel plants to improve sulfur use efficiency: living instruments for nondestructive analysis Bhakti Prinsi (Milan) Modulation of root glutamine synthetase isoforms and plant amino acid balance in response to nitrogen nutrition in maize Vladimir Totev Valkov (Naples) Systematic characterization of members of the L. Japonicus NPF family up-regulated in symbiotic nitrogen fixation nodules. What’s their role on nodule functioning? Laura Zanin (Udine) Transcriptional and physiological aspects of Fe deficiency response in roots of Zea mays Michela Zottini (Padua) Plant growth promotion effects of endophyte community associated to Vitis vinifera cv. Glera

Saturday, 27 September

9:00-11:00	Parallel Symposia II 1. Telomeres in model organisms: similarities and differences with human telomeres Chair: M. Gatti Maurizio Gatti (Rome) Introduction Maria Pia Longhese (Milan) Protection of telomeres: mechanisms and regulation in S. cerevisiae Giovanni Cenci (Rome) Organization and evolution of Drosophila telomeres Miguel Godinho Ferreira (Oeiras, Portugal) Zebrafish telomerase is required for normal lifespan and cancer 2. Plant-soil relationships as key factors for food security and sustainability Chairs: Roberto Pinton, Matteo Lorito Paolo Nannipieri (Florence) Omics approaches to unravel plant-soil relationships Pascal Simonet (Lyon, France) Soil Metagenomics: state of the art/The role of bacterial transformation in the rhizosphere Matteo Lorito (Naples) Soil-borne beneficial microbes that improve food security Graziano Zocchi (Milan) The long and winding road of iron from soil to seed 3. Population genomics Chair: G. Destro Bisol Mark Jobling (Leicester, UK) Sex-specific histories from targeted resequencing of human and great ape genomes Paolo Francalacci (Sassari) Refining the human Y-chromosome tree using phylogenetically informative SNPs from the whole euchromatic region (23.1 Mbp) Luca Pagani (Cambridge, UK) Inferences on worldwide human diversity from a panel of 450 high coverage whole genome sequences Enza Colonna (Naples) Extreme pattern of genetic diversity in humans
11:00-11:30	Coffee break
11:30-12:30	Plenary Lecture 4 Johannes Krause (Tuebingen, Germany) Genomic analysis of pre-contact Mycobacterium tuberculosis from the new world
	Closing Remarks/Awards by Felice Cervone

The poster's maximum size is 90 x 130 cm (width x height).

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Poster Session I
Poster Session II

1. Metabolism and its regulation in health and diseases

8. Nutrition Biochemistry

3. Genomics, Proteomics and System Biology

23. Transcription Mechanisms and Networks

10. Human Genetic and Genomic Diversity

12. Evolution

9. Epigenetics and Epigenetic Therapies

24. Noncoding RNA

15. Oncogenes and Tumor suppressors

22. Environmental and Molecular Mutagenesis

17. Immunology and Host-Pathogen Interaction

18. Plant Development and Disease

P1.1

Hepcidin binding to ferroportin prevents exocrine pancreatic failure and fatal iron overload

Sandro Altamura · Heidelberg, Germany

P1.2

Platelet-activating factor acetylhydrolase, paraoxonase 1 and oxidized low density lipoproteins in Alzheimer’s disease patients and elderly subjects

Tiziana Bacchetti · Ancona

P1.3

Silencing of FLAD1 gene affects neuromuscular transmission in Caenorhabditis elegans

Maria Barile · Bari

P1.4

Modeling human coasy mutation in yeast saccharomyces cerevisiae

Camilla Ceccatelli Berti · Parma

P1.5

Serglycin knockdown reduces inflammatory response in articular murine chondrocytes stimulated with LPS

Angela D'Ascola · Messina

P1.6

Might Cterm LeuRS peptide sequences be used to rescue defects due to mitochondrial tRNA mutations?

Mario Fazzi D'Orsi · Rome

P1.7

Class I histone deacetylases: key players in the pathophysiology of metabolic disorders

Alessandra Ferrari · Milan

P1.8

Regulation of NADPH cytochrome P450 oxidoreductase by 1,25-dihydroxyvitamin D₃and all-trans retinoic acid in acute myeloid leukemia cells

Elzbieta Gocek · Wroclaw, Poland

P1.9

Overexpression of superoxide dismutase 1 in yeast devoid of endogenous porin: effect on mitochondria and oxidative stress

Andrea Magrì · Catania

P1.10

The pyruvate carrier, main mitochondrial substrate transporter. From early functional characterization to recent finding of pathological gene mutations.

Sergio Papa · Bari

P1.11

Impaired Nrf2/ARE system contributes to SRB1 loss, as consequence of oxidative post-translational modifications, in CDKL5 atypical Rett syndrome

Alessandra Pecorelli · Siena

P1.12

Novel synthetic thyronamines as new powerful tools to explore the physiological function of TAAR1

Martina Sabatini · Pisa

P1.13

Folate metabolism and Alzheimer’s Disease

Pierpaola Tannorella · Pisa

P1.14

miRNAs: a connection between fatty acid metabolism and cancerogenesis in prostate cells

Anna Valentino · Naples

P8.1

Effect of gender on platelet serotonin transporter expression in class III obese individuals

Laura Betti · Pisa

P8.2

Effect of feeding on plasma serotonin and tryptophan levels in untrained horses

Alida Ferlazzo · Messina

P8.3

Functional characterization of a recombinant maize allergenic chitinase

Giuseppina Galante · Bari

P8.4

Inhibitory effects of different catechin formulations on tumor cells

Martina Giannaccini · Pisa

P8.5

In vitro modulation of pancreatic insulin secretion, extrapancreatic insulin action, and peptide glycation by Curcuma longa aqueous extracts

Violet Kasabri · Amman, Jordan

P8.6

Bioactive peptides with cardiovascular protective activity from wheat grains

Emanuela Leoncini · Rimini

P8.7

Cardio and vascular protective activities of Olea Europea and Hibiscus extratcs

Marco Malaguti · Rimini

P8.8

Nutraceutical properties of Tuscan chestnut flours: beneficial effects on skeletal muscle atrophy.

Elisabetta Meacci · Florence

P8.9

In vitro assessment of Novel nutraceutical formulation: hepatocyte based model exploiting time lapse video-microscopy

Antonietta Stellavato · Naples

P8.10

Characterization and evaluation of potential anti-angiogenic activity of tomato miniproteins and lycopene

Davide Treggiari · Verona

P3.1

New insights into protamine-like component organization in Mytilus galloprovincialis sperm chromatin

Stefano Avagnano · Naples

P3.2

Juglans regia L. genotypes identification by single nucleotide polymorphisms

Petronia Carillo · Caserta

P3.3

Retrotransposon copy number variation between wild and cultivated sunflowers

Andrea Cavallini · Pisa

P3.4

The inflorescence transcriptome of Orchis italica, a wild Mediterranean orchid species

Sofia De Paolo · Naples

P3.5

Landscape genomics reveals environmental adaptation in Turkish Brachypodium distachyon natural populations

Matteo Dell'Acqua · Pisa

P3.6

Comparative proteomic analysis of malignant pleural mesothelioma: focusing on the biphasic subtype

Antonio Lucacchini · Pisa

P3.7

Genetic and molecular analysis of the cross-incompatibility phenomenon in maize

Husna Nugrahapraja · Pisa

P3.8

From genome to phenome and back: understanding the high metabolic versatility of Burkholderia cepacia complex

Elena Perrin · Sesto Fiorentino (FI)

P23.1

454 pyrosequencing and de novo assembly of Antarctic krill (Euphausia superba) transcriptome

Alberto Biscontin · Padua

P23.2

Tab2 controls ERα complexes and resistance to endocrine therapy

Michele De Bortoli · Orbassano

P23.3

The Cop9 signalosome is involved in the regulation of lipid metabolism and of transition metals uptake in S. cerevisiae

Rodolfo Negri · Rome

P23.4

Functional studies of Mesorhizobium loti proteins

Alessia Rivellino · Caserta

P10.1

When data sharing gets close to 100%: what ancient human DNA studies can teach to the open science movement

Paolo Anagnostou · Rome

P10.2

Expression status of candidate genes in mesothelioma tissues and cell lines

Elisa Barone · Pisa

P10.3

Traces of Medieval migrations in a socially-stratified population from Northern Italy. Evidence from uniparental markers and deep-rooted pedigrees

Alessio Boattini · Bologna

P10.4

Identification and genomic characterization of HERV-K (HML-10) in human genome GRCh37/hg19 assembly

Marta Cadeddu · Monserrato (CA)

P10.5

Could nucleoporins be involved in susceptibility to endometriosis?

Monica Cipollini · Pisa

P10.6

Modern alpine populations have no maternal lineages related to the Tyrolean Iceman

Valentina Coia · Bolzano

P10.7

Genetic diversity in Amazonian indigenous people from Peru': data from Y-chromosome and mitochondrial DNA

Tullia Di Corcia · Rome

P10.8

Novel genome-wide association study-based candidate loci for differentiated thyroid cancer risk

Gisella Figlioli · Pisa

P10.9

Ancient human migrations from Arabia to Eastern Africa: new clues from R0a mitogenomes

Francesca Gandini · Pavia

P10.10

The origin of modern Panamanians: the Y-chromosome perspective

Viola Grugni · Pavia

P10.11

Folate metabolism and gene promoter methylation in thymomas of patients affected by Myasthenia Gravis

Angela Lopomo · Pisa

P10.12

Are MSLN, CFB and CCNO cancer genes of mesothelioma?

Ombretta Melaiu · Pisa

P10.13

Genetic analysis of the 16 STR loci for human identification in native Amazonian populations from Perù

Francesco Messina · Rome

P10.14

Population analyses of ancient Umbrians through a Next Generation Sequencing approach

Alessandra Modi · Florence

P10.15

Charting the most likely geographical origin of maternal and paternal human lineages in mixed Ecuadorian populations

Giuseppina Primativo · Rome

P10.16

Early human dispersal from Africa: a model-based test of two hypotheses

Francesca Tassi · Ferrara

P10.17

MiR34a oncosuppressor function in paediatric embrional tumors

Massimo Zollo · Naples

P12.1

Parallel domestication of common bean in Mesoamerica and Andes

Elisa Bellucci · Ancona

P12.2

Phylogenetic analysis of β-glucuronidases genes in Angiosperms

Giorgio Binelli · Varese

P12.3

New insights into the characterization of the ancestral centromere on human chromosome 2

Giorgia Chiatante · Bari

P12.4

Seeing through the skin: dermal light sensitivity provides cryptism in moorish gecko

Francesco Itri · Naples

P12.5

Genetic peculiarities of the wild boar in Italy

Hovirag Lancioni · Perugia

P12.6

Bayesian inference of Pan evolutionary history inferred from complete mitochondrial genomes

Serena Tucci · Ferrara

P12.7

Genetic structure of Cistus albidus, a Mediterranean shrub characterised by habitat fragmentation

Isabella Vanetti · Varese

P9.1

Social defeat stress alters the expression of psychiatric disorders related genes in mouse brain cortex

Lorenzo Chiariotti · Naples

P9.2

Nhp6 as regulator of gene transcription

Francesca Di Felice · Rome

P9.3

Spreading Depolarization in nervous cells:DNA methylation and Preconditioning phenomenon

Denise Drongitis · Naples

P9.4

Unexpected genome-wide DNA methylation stability across plant populations adapted to divergent habitats

Emiliano Trucchi · Vienna, Austria

P24.1

Post-transcriptional regulation of PHOX2B gene expression

Tiziana Bachetti · Genoa

P24.2

miR-17-92 counterbalances MYC and fine-tunes MYC-centred regulatory networks in lymphoma maintenance

Tiziana Bonaldi · Milan

P24.3

A common polymorphism within MSLN affects miR-611 binding site and is associated with serum mesothelin (SMRP) in healthy people

Chiara De Santi · Pisa

P24.4

Identification of sRNA networks and their role in regulating virulence of Neisseria meningitidis

Giacomo Golfieri · Siena

P24.5

miRVine: a microRNA expression atlas of grapevine based on small RNA library sequencing

Erica Mica · Fiorenzuola d'Arda

P15.1

Oncogenic-promoting activity of 14-3-3θ in t(4;11) acute lymphoblastic leukemia

Tiziana Fioretti · Naples

P15.2

∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites

Paola Monti · Genoa

P15.3

KLF7 regulates TUBB3 gene expression in ovarian cancer

Simona Mozzetti · Rome

P15.4

Role of the ferritin heavy chain (FHC) in CXCR4/CXCL12 pathway

Mariafranca Panebianco · Catanzaro

P15.5

An atypical ligand for the fourth PDZ domain of Scribble

Simona Panni · Arcavacata di Rende (CS)

P15.6

The transcriptional factor EGR1 regulates the expression of nucleolar proein B23

Donatella Ponti · Latina

P15.7

ZEB2 gene expression is regulated by the RNA binding protein HuR and correlates with prognosis in ovarian cancer

Silvia Prislei · Rome

P15.8

New non canonical functions for human dyskerin

Ida Stufa · Naples

P22.1

Titanium dioxide nanoparticles. A potential use in polluted environment remediation

Margherita Bernardeschi · Pisa

P22.2

Effects of copper and nickel on protamine-like and on DNA oxidative damage in Mytilus galloprovincialis

Filomena Caccavale · Naples

P22.3

Influence of titanium dioxide nanoparticles on 2,3,7,8-tetrachlorodibenzo-p-dioxin and cadmium genotoxicity in the marine fish European sea bass (Dicentrachus labrax). A Trojan horse effect?

Patrizia Guidi · Pisa

P22.4

Cadmium effects on protamine-like and on DNA oxidative damage in Mytilus galloprovincialis

Francesca Pollice · Naples

P22.5

Effect of crystal habit on silica particle genotoxicity in human and murine cell lines

Vittoria Scarcelli · Pisa

P22.6

Characterisation of RNA-editing deficient DNA-editing proficient mutants of the RNA editing enzyme APOBEC1

Francesco Severi · Florence

P22.7

In vitro risk assessment of pure trans-anethole and of a herbal extract from Foeniculum vulgare (fennel), containing trans-anethole

Samuele Vannini · Perugia

P22.8

The MAPEC_LIFE study (LIFE12 ENV/IT/000614): monitoring air pollution effects in children for supporting public health policy

Marco Verani · Pisa

P22.9

Genotoxicity detection and flow cytometric evaluation of TiO₂ nanoparticles in human PBMC

Andrea Zijno · Rome

P17.1

Anti-Pseudomonal activity of the amphibian antimicrobial peptide Esculentin(1-21) and plausible mode of action

Vincenzo Luca · Rome

P17.2

Pseudomonas aeruginosa adaptation to the host as a strategy to evade immune system responses

Ida Paciello · Rome

P17.3

Sensitivity to infections of four silkworm Bombyx mori strains with different geographical origin

Ottavia Romoli · Padua

P18.1

NMR investigation of random coil regions: clues to assess the different biological activity of two cerato platanin family members

Fabio Baroni · Parma

P18.2

Characterization of cell wall traits of spikes from wheat lines resistant and susceptible to Fusarium graminearum

Daniela Bellincampi · Rome

P18.3

The phytotoxin fusicoccin is a general regulator of the interaction of 14-3-3 proteins with their protein targets

Lorenzo Camoni · Rome

P18.4

Pectic enzymes in the oomycetes pathogenesis

Claudio Caprari · Pesche (IS)

P18.5

Petunia MAEWEST and MAEWESTb functionally overlap in promoting lateral development of floral organs

Enrico Costanzo · Lyon, France

P18.6

Assessment of antitumor and antimutagenic activity of saponin fractions from Astragalus verrucosus

Maria Sole Facioni · Pisa

P18.7

Characterization of Arabidopsis LysM receptors involved in plant innate immunity

Simone Ferrari · Rome

P18.8

Has Trichoderma harzianum 6776 beneficial effects on different cultivation system?

Lisa Fiorini · Pisa

P18.9

The functional characterization of a putative acetylornithine deacetylase of Arabidopsis thaliana reveals its role in flowering time and fruit set

Barbara Molesini · Verona

P18.10

Study of the role of type III LTPs during the symbiotic interaction between Sinorhizobium meliloti and Medicago truncatula

Chiara Santi · Verona

2. Cellular Stress, apoptosis and autophagy

21. Protein Synthesis, Degradation and Homeostasis

6. Development, Differentiation and Aging

16. Stem Cells, IPS, Cancer Stem Cells

7. Environmental Microbiology and Biotechnology

11. Genetic of Microorganisms

4. Chromosome Biology, Cell Division and Cell Cycle

5. DNA replication, Repair and Recombination

13. Neurobiology

14. Cell Communication, Cell Adhesion and Membrane Trafficking

19. Plant Metabolism and Environmental Stress

20. Plant Nutrition

P2.1

Combinations of cytotoxic and pro-autophagic compounds against melanoma cells

Giulia Allavena · Siena

P2.2

Changes in SAM2 expression affect lactic acid tolerance and lactic acid production in Saccharomyces cerevisiae

Nadia Berterame · Milan

P2.3

The HDAC inhibitor SAHA synergistically stimulates the cytotoxic effect induced by Parthenolide in MDA-MB231 cells

Daniela Carlisi · Palermo

P2.4

Recruitment of MyD88 in the early phases of HSV-1 infection

Maria Grazia Ceraolo · Messina

P2.5

Expression of the animal pro-apoptotic protein Bid in Arabidopsis thaliana

Massimo Crimi · Verona

P2.6

The human RNASET2 tumor antagonizing gene as a novel stress-response gene potentially involved in microenvironment-mediated tumor suppression

Marta Lualdi · Varese

P2.7

Apoptosis induced by HSV-1 requires BH3-only protein Puma and p73

Francesca Marino-Merlo · Messina

P2.8

Involvement of TOP I and PARP inhibitors in the p53/p63-dependent cell fate decision between growth arrest and apoptosis.

Daniela Montariello · Naples

P2.9

Modulation of mitochondrial Ca⁺² and Mg⁺² dependent F₁F_O-ATPase by nitrite

Salvatore Nesci · Ozzano Emilia

P2.10

Deregulation of miRNAs is linked to p21 proapototic role

Maria Teresa Piccolo · Atripalda (AV)

P2.11

Characterization of recombinant human VDAC3: a VDAC forming small pores

Simona Reina · Valverde

P2.12

F₂-Isoprostanes play a role in Bleomycine-induced lung fibrosis

Blerta Stringa · Siena

P2.13

Ferritin heavy chain silencing, ROS production and protein misfolding in K562 cells

Fabiana Zolea · Catanzaro

P21.1

The role of Drosophila pseudouridine synthase component of H/ACA snoRNPs in compensatory proliferation and tissue remodeling

Annamaria Di Giovanni · Naples

P21.2

Structural and functional characterization of crested porcupine (Hystrix cristata L.) and reindeer (Rangifer tarandus L.) myoglobins.

Antonella Maria Assunta Di Giuseppe · Caserta

P21.3

Molecular mechanisms of tonoplast protein degradation

Clarissa Lancilli · Milan

P21.4

The dual role of the p300 acetyl transferase protein on ΔNp63α stability

Alessia Tramontini · Milan

P6.1

Generation and characterization of a novel zebrafish reporter line for cAMP/CREB signaling

Giorgia Busolin · Padua

P6.2

Translational regulation in Drosophila spermatogenesis: the role of the DEAD-box RNA helicase Belle

Nadia Formicola · Naples

P6.3

Lack of FCD-2 protein during development induces developmental defects in Caenorhabditis elegans

Marcello Germoglio · Naples

P6.4

Effects of natural compounds present in Chelidonium majus on stem cells and embryo development

Maria Emilia Isolani · Pisa

P6.5

Impact of forced inclusion or exclusion of Extra Domain A (EIIIA) exon of fibronectin on adult murine hemopoiesis

Alessandro Malara · Pavia

P6.6

Potential involvement of pdzrn3 gene during kidney morphogenesis

Silvia Marracci · Pisa

P6.7

The transcription factor Nfix regulates the proper timing of post-natal muscle growth and regeneration

Graziella Messina · Milan

P6.8

P63, a new molecular target of the teratogenic drug Thalidomide

Elisa Molinari · Milan

P6.9

FGF8, c-Abl and p300 cooperate in the regulation of ΔNp63α protein stability

Michela Restelli · Milan

P6.10

RNA-seq and Insect pests: new methods for the identification and the analysis of sex-specific genes in species of economic or sanitary interests

Marco Salvemini · Naples

P6.11

microRNA-494 promotes cellular senescence in Human Diploid Fibroblasts by targeting several genes

Mariangela Succoio · Naples

P6.12

Nerve Growth Factor (NGF) and its receptor level correlates with Osteoarthritis progression: implication with Matrix Metalloproteinase secretion in synovial fluid

Roberto Tiribuzi · Arezzo

P16.1

Mesenchymal stromal cell secreted sphingosine 1-phosphate exerts a stimulatory effect on skeletal myoblast proliferation

Alessia Frati · Florence

P16.2

Dynamic intracellular localization of natural alkaloids in different human tumor cell lines: a case study with berberine

Marco Natali · Pisa

P16.3

SOX2 is critical for human melanoma initiating cells

Silvia Pietrobono · Florence

P16.4

Sialidase NEU4 inhibition reduces glioblastoma stem cell renewal

Francesca Testa · Segrate

P16.5

Human osteosarcoma 3AB-OS cancer stem cells is a model to study microRNA-29b-1 involvement in self-renewal and fate decisions of stem cells

Renza Vento · Palermo

P7.1

Increased mitochondrial pyruvate dissimilation in yeast

Gennaro Agrimi · Bari

P7.2

New technologies and tools for second generation bioethanol production: the BIOASSORT project

Antonella Amore · Naples

P7.3

Persistance and effect on the soil native community of a mycorrhizal fungi-based Inoculum in the rhizosphere of maize plants

Valeria Bianciotto · Turin

P7.4

Frequency of heavy metal and antibiotic resistance in enterococci isolated from coastal marine sediments

Francesca Biavasco · Ancona

P7.5

A world inside a glass of drinking water: community analysis and dynamics of antibiotic resistance genes

Antonia Bruno · Milan

P7.6

Bi-fuel supply is adopted by Rhodobacter sphaeroides to cope with high concentrations of Cobalt ions

Luigi Ceci · Bari

P7.7

Conversion of the genotoxin 4-nitroquinoline-1-oxide into inactive products by a probiotic Lactobacillus rhamnosus strain

Giovanni Cenci · Perugia

P7.8

Genomic and phenotypical characterization of the electroactive bacteria Enterobacter sp. EAN3: preliminary results

Carolina Chiellini · Florence

P7.9

Phytoremediation by algae: a step of a multi-stage biotechnological process of bioremediation of an hydrocarbon sludge

Adriana Ciurli · Pisa

P7.10

Impact of desert dust deposition on the bacterial community of mountain glacier snow.

Ermanno Federici · Perugia

P7.11

Characterization and monitoring of a microbial community responsible of an innovative biological process for sulfide removal from industrial waste

Cesira Giordano · Pisa

P7.12

Essential oils: possible use to fight Burkholderia cepacia complex strains

Isabel Maida · Florence

P7.13

A rapid method to improve selection of cellular clones targeted by the CRISPR/Cas9 system

Francesca Niccheri · Florence

P7.14

Screening of thiosemicarbazones as antimycotic drugs

Cecilia Nolli · Parma

P7.15

TALEs for every season: targeted DNA damage and live visualisation of DNA

Riccardo Pecori · Florence

P7.16

Mycobacterium smegmatis as model system to investigate cell wall components in nontuberculous Mycobacteria

Filomena Perrone · Caserta

P7.17

Antibacterial, antifungal and antitumor activity of Mytilus galloprovincialis’ protamine-like

Marina Piscopo · Naples

P7.18

Regulatory and metabolic proteins differentially expressed during NAI-107 production in Microbispora sp. ATCC-PTA 5024

Anna Maria Puglia · Palermo

P7.19

In planta heterologous expression of thermophilic enzymes for the degradation of the plant cell wall

Anthony Rosa · Verona

P7.20

Testing PhyloH, a new phylogenetic approach on diversity analyses of bacterial communities

Anna Sandionigi · Milan

P7.21

Isolation and characterization of a microbial consortium capable to deplete total petroleum hydrocarbon in dredged sediments

Giovanna Siracusa · Pisa

P7.22

Chemical-physical and biological removal of oily compounds from slops originated from oil transportation by tankers

Anna Volta · Messina

P7.23

Stimulation of hydrocarbons biodegradation in a marine sediment contaminated by crude oil with biogenic pollutant mobilizing agents and biosurfactants

Giulio Zanaroli · Bologna

P11.1

Analysis of intestinal microbial biodiversity in newborns exposed to intrapartum antibiotic prophylaxis by means of a massive sequencing approach

Sara De Fanti · Bologna

P11.2

Genetic, physiological and molecular characterization of MPV17/SYM1 mutations in Saccharomyces cerevisiae

Ileana Ferrero · Parma

P11.3

Systems biology analysis of Helicobacter pylori heat-shock response: dissecting complex multi-layered regulatory strategies of gene expression

Elisabetta Fiore · Bologna

P11.4

Investigating new pathoadaptive mutations in Shigella and EIEC strains given rise to the interaction with host cells

Adriano Leuzzi · Rome

P11.5

Abiotic signal transduction pathways in the classical eukaryotic model system: yeast

Marco Proietto · Rome

P11.6

Characterization of gut microbiome and mycobiome in patients with Rett syndrome

Francesco Strati · San Michele all'Adige

P4.1

Molecular and cytogenetic characterization of cell lines mutant in the dyskerin gene

Paola Leopardi · Rome

P4.2

p14^ARF reduces aneuploidy induced by CENPE post-transcriptional silencing

Lorena Veneziano · Palermo

P4.3

Importin beta as a global regulator of mitosis

Annalisa Verrico · Rome

P5.1

Fine regulation of DNA damage apoptosis in C. elegans meiosis

Adele Adamo · Naples

P5.2

Myc suppression of DNA double-strand break repair

Susanna Ambrosio · Naples

P5.3

Interplay between Werner syndrome protein (WRN) and the ATR-checkpoint in preserving genome integrity at common fragile sites

Giorgia Basile · Rome

P5.4

Effect of the telomeric G-quadruplex ligand RHPS4 in NHEJ-proficient (M059K) and -deficient (M059J) glioblastoma cell lines

Francesco Berardinelli · Rome

P5.5

A cell culture comparative biology approach to study mechanisms of genome stability and their relevance for species longevity: a newer interpretation of DNA damage induced nuclear foci.

Martine Bocchini · Bologna

P5.6

A rapid and cost-effective assay to measure functional activity of Base Excision Repair enzymes in cell extracts

Caterina Cerasaro · Rome

P5.7

Oncogenic disruption of promyelocytic leukemia nuclear bodies results in defective DNA double strand breaks sensing and repair

Domenica Cilli · Rome

P5.8

An oxidized dNTPs pool and aberrant repair synthesis contribute to GAC/CTG repeat instability

Piera Cilli · Rome

P5.9

Mycobacterium tuberculosis: investigation of the adaptive response

Pamela di Pasquale · Naples

P5.10

p21 regulates the affinity of PARP-1 for damaged DNA

Ilaria Dutto · Pavia

P5.11

A novel role for the WRN exonuclease activity: processing and protection of reversed forks from MRE11-mediated degradation

Chiara Iannascoli · Rome

P5.12

A novel role for the Werner helicase-interacting Protein 1 in protecting genome integrity during DNA replication

Giuseppe Leuzzi · Rome

P5.13

MUS81 and GEN1 nucleases are involved in DSBs formation after CHK1 inhibition

Eva Malacaria · Rome

P5.14

Activity of AID driven by cell cycle specific promoters

Giorgio Mattiuz · Florence

P5.15

Somatic mutations patterns in colorectal cancer patients affected by MUTYH-associated polyposis

Ettore Meccia · Rome

P5.16

MUS81 phosphorylation by CHK2 is required for its efficient activation during S- and G2/M phases of cell cycle

Ivana Murfuni · Rome

P5.17

Functional analysis of the putative FHA-binding site of MUS81 during replication

Anita Palma · Rome

P5.18

Isolation of mutants suppressing fcd-2 phenotypes in Caenorhabditis elegans

Pamela Santonicola · Naples

P13.1

Leigh Syndrome in Drosophila melanogaster: morphological and biochemical characterization of Surf1 post-transcriptional silencing

Cristiano De Pitta · Padua

P13.2

The role of Huntingtin in EGFR pathway of non-neuronal cells: evidences in a Drosophila Melanogaster model of Hungtinton Disease

Mauro Finicelli · Naples

P13.3

Neuroprotective effects of two creatine salts in brain hippocampal slices

Patrizia Garbati · Genoa

P13.4

period and timeless mRNA splicing profiles under natural conditions in Drosophila melanogaster

Gabriella Mazzotta · Padua

P13.5

Morning serum melatonin in patients with mood disorders and insomnia: influence of age, body mass index, smoke and photoperiod

Lionella Palego · Pisa

P13.6

Unstable dendritic spines in a mouse model of CDKL5 disorder

Tommaso Pizzorusso · Pisa

P13.7

Delivery of a neuroprotective cell-penetrating Hsp70

Loredano Pollegioni · Varese

P13.8

Magnetic nanoparticles can direct axonal growth

Vittoria Raffa · Dundee, United Kingdom

P13.9

Engineering membrane models capable to target β-amyloid and to modulate its aggregation features: implications for therapy of Alzheimer’s disease

Francesca Re · Monza

P13.10

Enhanced expression of amyloid precursor protein in platelets from patients with Alzheimer’s Disease and Frontotemporal Lobar Degeneration

Davide Sartini · Ancona

P13.11

CLIC1 is relevant for exosome-dependent growth of glioma cells

Matteo Setti · Milan

P13.12

A P2X7 antagonist improves muscle strength and motor distal amplitude in CMT1A rats: preliminary results from an in vivo trial

Giovanna Sociali · Genoa

P14.1

Electrical activity dependent cx43 acetylation: a new mechanism for regulating cardiomyocyte communication

Valerio Azzimato · Rome

P14.2

Quantification of tissue T3, T4 and their metabolites in rat and human tissues by a novel HPLC-MS/MS method

Riccardo Donzelli · Pisa

P14.3

Plasma membrane sialidase NEU3 controls epithelial-mesenchymal transition in melanoma cells

Ilaria Silvestri · Segrate

P14.4

AQP8 facilitates Nox-produced hydrogen peroxide transport in leukaemia cells

Francesco Vieceli Dalla Sega · Bologna

P19.1

Transcriptomic analysis of light response in Nannochloropsis gaditana highlights the basis for specific metabolic remodeling

Alessandro Alboresi · Padua

P19.2

Understanding cell wall re-modelling during mycorrhizal symbiotic interactions

Raffaella Balestrini · Turin

P19.3

Salts modulate δ¹-pyrroline-5-carboxylate metabolism in rice

Michele Bertazzini · Ferrara

P19.4

Molecular networks controlling leaf cell differentiation during drought stress in Brachypodium distachyon

Edoardo Bertolini · Pisa

P19.5

The PSI peripheral antenna is crucial for acclimation of Arabidopsis thaliana to changing light conditions

Mauro Bressan · Verona

P19.6

Organ specificity of Strigolactone production in tomato plants under osmotic stress

Francesca Cardinale · Grugliasco (TO)

P19.7

Enhanced production of bioactive compounds in plant cell suspension cultures of Artemisia annua L.

Sofia Caretto · Lecce

P19.8

Molecular and technical advances for the in vivo analysis of Ca²⁺ dynamics in plant cells

Alex Costa · Milan

P19.9

Evaluation of new synthesized “adenosine derivatives” molecules as cytokinin-like compounds

Francesca D'Angiolillo · Pisa

P19.10

The importance of osmoregulation and ionic effects on xylem hydraulics in the invasive halophyte Spartina patens (Ait.) Muhl

Valentina De Col · Udine

P19.11

The effects of heavy metals exposition on the activity of recombinant plant plastidic glucose 6P dehydrogenase

Alessia De Lillo · Naples

P19.12

Identification and molecular characterization of the sucrose synthase 2 gene in durum wheat

Immacolata Fanizza · Bari

P19.13

Evolutionary role of a vacuolar metal transporter for hypertolerance/hyperaccumulation in Arabidopsis halleri

Elisa Fasani · Verona

P19.14

Proline metabolism in salt-shocked versus salt-adapted rice seedlings

Giuseppe Forlani · Ferrara

P19.15

Peroxydase and polyphenoloxidase activities and isoforms distribution in fruits of sweet cherry from Campania Region (Italy)

Amodio Fuggi · Caserta

P19.16

High-level expression of Physcomitrella patens light harvesting complex stress related protein 1 (LHCSR1) protein by transient expression in Nicotiana benthamiana

Leonardo Ghin · Verona

P19.17

Metal adaptation can affect the response to biotic stress in higher plants: a study on Silene paradoxa L.

Cristina Gonnelli · Florence

P19.18

Leaf water relation traits in typical Sicilian varieties of Vitis vinifera L.

Simone Inzerillo · Palermo

P19.19

Phenotypic plasticity of Mediterranean oak species in response to combined ozone and drought stress

Marco Landi · Pisa

P19.20

Changes in the levels of HSP70 in relation to heavy metals exposition in Elodea canadensis

Marco Lentini · Naples

P19.21

Interplay between cGMP and redox signalling under biotic stress

Vittoria Locato · Rome

P19.22

Aquaporin involvement in controlling leaf hydraulic capacitance and resistance

Claudio Lovisolo · Grugliasco (TO)

P19.23

Rooting depth as a key trait connecting water and carbon metabolism of trees

Andrea Nardini · Trieste

P19.24

Potassium deficiency and drought stress in grapevine cultivars

Elisabetta Oddo · Palermo

P19.25

Defense response to fungal pathogens in susceptible and resistant maize genotypes

Costantino Paciolla · Bari

P19.26

Novel putative miRNAs in different graft combinations of grapevine upon drought

Chiara Pagliarani · Grugliasco (TO)

P19.27

Metabolite transport pathways in durum wheat mitochondria from hyperosmotically-stressed seedlings

Donato Pastore · Foggia

P19.28

Redox status of the pyridine nucleotide pools and proline synthesis in tobacco

Davide Petrollino · Ferrara

P19.29

Redox regulated β-amylase 1 (BAM1) is inhibited by glutathionylation

Claudia Pirone · Bologna

P19.30

Phytoremediation potentiality of Cistus ssp. and Inula viscosa in heavy metal contaminated soils

Laura Pistelli · Pisa

P19.31

Redox regulation of algal ATP sulfurylase

Laura Prioretti · Ancona

P19.32

Biochar amendment improves lettuce quality in metal-contaminated soils

Mike Quartacci · Pisa

P19.33

Flax seed and its by-product as a source of secondary metabolites

Annamaria Ranieri · Pisa

P19.34

Xylem cavitation and hydraulic degradation portend increasing risks of tree mortality under climate change scenarios

Tadeja Savi · Trieste

P19.35

UV-B post-harvest irradiation is effective in increasing the level of antioxidants of peaches during a brief refrigerated storage

Claudia Scattino · Pisa

P19.36

The response of Arabidopsis thaliana to mild osmotic stress involves primary starch metabolism and is triggered by the activation of the redox sensitive ß-amylase 1 (BAM1)

Francesca Sparla · Bologna

P19.37

iTRAQ analysis of the molecular dialogue between an arbuscolar mycorrhizal fungus and its endosymbiotic bacteria

Lorenzo Testa · Varese

P19.38

Photosynthetic response to nitrogen starvation and high light in Haematococcus pluvialis

Matteo Ballottari · Verona

P19.39

Does F_OF₁ ATP synthase form the mitochondrial permeability transition pore in plants?

Marco Zancani · Udine

P19.40

Rare earth elements: resources or pollutants?

Maria Alessandra Zicari · Bari

P20.1

Nitrate control of nodule formation in Lotus japonicus: functional characterization of a low affinity nitrate transporter

Ludovico Alves · Naples

P20.2

Potassium deficiency and drought stress in grapevine cultivars

Martina Calabrese · Palermo

P20.3

The interplay between photorespiration and iron deficiency: a preliminary investigation.

Fabio Marco Casiraghi · Milan

P20.4

Molecular characterization of two cation transporters of Arabidopsis thaliana

Silvia Piasentin · Verona

P20.5

Comparative study on physiological and transcriptional responses to iron and phosphorus deficiency in roots of Lupinus albus L.

Roberto Pinton · Udine

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Registrations
& Payment

1 April 2014

13 August 2014

Only on-site registrations will be accepted after the deadline, at a higher fee. Check the Information page for further details.

Abstracts

1 April 2014

1 July 2014
New deadline

Notification of abstract selections:
25 July 2014

Contacts

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